Long Covid presents a complex immune dysfunction characterized by simultaneous hyperactivity and hypoactivity, leading to inflammation, immune exhaustion, autoimmunity, and reactivation of latent viruses. Patients face chronic immune dysregulation, resulting in persistent fatigue and increased vulnerability to infections. Understanding these interconnected mechanisms is crucial for effective management and treatment.
Tag: immune dysregulation
Immunotherapy for Long COVID: IVIG, Rituximab and Monoclonal Antibodies Explained
IVIG, rituximab and monoclonal antibodies are increasingly discussed as possible Long Covid treatments. Here is what the evidence shows, why access remains difficult and what researchers still do not know.
Decoding ME/CFS: Key Genetic Findings Explained
Recent genetic research has confirmed that Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a biological condition, not merely psychological. The DecodeME study identified eight genetic signals linked to the immune and nervous systems, validating patient experiences. Understanding this can aid healthcare discussions, allowing for better management and support for those affected.
Can Monoclonal Antibodies Help Long COVID? What the Latest Research Really Shows
Can monoclonal antibodies help Long COVID? Learn how these targeted medicines work, why researchers are studying Sipavibart, Pemgarda and Evusheld, and what current evidence says about viral persistence, NHS access and future treatments.
Role of Galectin-3 in Long COVID Symptoms
Galectin-3 is an inflammatory protein being investigated as a possible contributor to Long COVID. Learn how it may interact with microclots, inflammation and immune dysfunction, and why researchers see it as a promising but still experimental treatment target.